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2020 | 4 |
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Page 1
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly.
Nat Commun. 2020 May 1;11(1):2147. doi: 10.1038/s41467-020-16096-w.
Nat Commun. 2020.
PMID: 32358495
Free PMC article.
Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens.
Clements KE, Schleicher EM, Thakar T, Hale A, Dhoonmoon A, Tolman NJ, Sharma A, Liang X, Imamura Kawasawa Y, Nicolae CM, Wang HG, De S, Moldovan GL.
Clements KE, et al.
Nat Commun. 2020 Nov 30;11(1):6118. doi: 10.1038/s41467-020-19961-w.
Nat Commun. 2020.
PMID: 33257658
Free PMC article.
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Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells.
Clements KE, Thakar T, Nicolae CM, Liang X, Wang HG, Moldovan GL.
Clements KE, et al.
Nucleic Acids Res. 2018 Sep 28;46(17):8898-8907. doi: 10.1093/nar/gky657.
Nucleic Acids Res. 2018.
PMID: 30032296
Free PMC article.
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Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in DNA replication dynamics controlled by ATR.
Dhoonmoon A, Schleicher EM, Clements KE, Nicolae CM, Moldovan GL.
Dhoonmoon A, et al. Among authors: clements ke.
Nucleic Acids Res. 2020 Jul 27;48(13):7252-7264. doi: 10.1093/nar/gkaa508.
Nucleic Acids Res. 2020.
PMID: 32542389
Free PMC article.
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Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors.
Schleicher EM, Dhoonmoon A, Jackson LM, Clements KE, Stump CL, Nicolae CM, Moldovan GL.
Schleicher EM, et al. Among authors: clements ke.
PLoS Genet. 2020 Nov 2;16(11):e1009176. doi: 10.1371/journal.pgen.1009176. eCollection 2020 Nov.
PLoS Genet. 2020.
PMID: 33137164
Free PMC article.
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